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From149US$ /night
Check-in
26Dec2025Select date
Check-out
27Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel overview and key features

43 Columbia Street, Orlando, Florida, United States, 32806
-
Near the city center
Great
8.9
9.1
/10
4.6
4.3
/5

Hampton Inn & Suites Orlando/Downtown South - Medical Center is a 3-star hotel near Orlando Executive Airport, located in Downtown Orlando, home to City Hall, modern office towers, and 19th-century buildings. The property is within walking distance of Arnold Palmer Hospital for Children and a 15-minute walk from Orange Avenue. Nearby attractions include Sodo Shopping Center (0.9 miles) and Lake Eola Park (1.6 miles).

Comfortable Accommodations

The 126 air-conditioned rooms at Hampton Inn & Suites Orlando/Downtown South - Medical Center feature two queen or one king-sized Hampton clean and fresh bed(R), flat-screen TVs, and coffee-making facilities. Select rooms include a lap desk, small refrigerator, and sofa bed. Accessible rooms with visual alarms, lowered beds, and roll-in showers are available.

Dining Options

A free hot breakfast buffet is served daily, with Hampton's On the Run Breakfast Bags available Monday through Friday. The snack bar/deli offers quick bites for guests on the go. Coffee/tea makers are provided in all rooms.

Recreation & Attractions

Guests can enjoy the outdoor pool and fitness center during their stay. The hotel's central location provides easy access to Universal Orlando Resort and The Wizarding World of Harry Potter(TM). Local staff offer friendly service and area advice.

Business Facilities

Hampton Inn Orlando Downtown South features 1128 square feet of conference space with LCD projector and free WiFi. The business center and dry cleaning services cater to working guests. Contactless Arrival is available through the Hilton Honors app.

“This hotel's proximity to the medical center and downtown Orlando makes it a practical choice. I especially note the exceptional service during breakfast. I think its pet-friendly policy and amenities like a fitness center enhance its appeal, even with a parking fee.”
Hotel logo
Amelia BrooksLead Hotel Editor at Hotelairport
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Choose your ideal room style

Choose from family rooms, suites, flexible cancellation & more
King Room Hearing Accessible
2 persons
36 m² 
1 King-size bed
Shower
Queen Room Two Queen Beds
2 persons
28 m² 
2 King Size Beds
Shower
King Room Non-Smoking
2 persons
33 m² 
1 King-size bed
Shower
King Room Sofa Bed Non-Smoking
2 persons
34 m² 
1 King-size bed and 1 Sofa bed
Shower
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Prices and Availability

Check availability and prices for your travel dates right now!

Facilities

Stay relaxed and refreshed just minutes from the airport

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Snack bar

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's buffet

Spa & Leisure

  • Outdoor swimming pool
  • Sun loungers
  • Leisure/ TV room

Room features

  • Air conditioning
  • Sitting area
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Media

  • Flat-screen TV
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Location info

43 Columbia Street, Orlando, Florida, United States, 32806
Map view
43 Columbia Street, Orlando, Florida, United States, 32806
Nearby
Amusement Park
Delaney Street Playground
540 m
Hospital
Orlando Regional Medical Center
300 m
Orlando Regional-Lucerne
430 m
Hospital
Winnie Palmer Hospital for Women and Babies
570 m
Restaurants
Delaney's Tavern
450 m
1315 S Orange Ave
Lucy Bleuz Cafe
530 m
1321 Sligh Blvd
Incredibly Edible
530 m
1321 Sligh Blvd
Orlando Brewing
670 m
1301 Atlanta Avenue
Brick & Fire
780 m
1621 S Orange Ave Ste 108
Pizza Hut
780 m
1621 S Orange Ave
Subway
950 m
1742 S Orange Ave
7-Eleven
1.1 km
1823 S Orange Ave
Explore Orlando
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Orange County Regional History Center
20 minutes' walk
Local history museum featuring exhibits on Orlando's past, with special events and guided tours available.
Lake Eola Park
30 minutes' walk
Scenic park known for its swan boats, walking paths, and the iconic fountain, perfect for picnics and family outings.
Mad Cow Theatre
20 minutes' walk
Performance venue showcasing a variety of theatrical productions, offering engaging shows in an intimate setting.
Amway Center
25 minutes' walk
Home to the Orlando Magic, this arena hosts sports events, concerts, and entertainment shows throughout the year.
Yoga at Lake Eola
30 minutes' walk
Outdoor yoga sessions available at Lake Eola. Ideal for relaxation and fitness, with sessions often scheduled in the mornings.
Biking along Orlando's Trails
15 minutes' drive
Biking trails around Orlando provide adventurous paths for thrill-seekers. Rentals are available nearby for ease.
Delaney's Tavern
6 minutes' walk
Casual dining with a warm atmosphere, featuring hearty pub fare and an extensive drink menu, perfect for families.
Orlando Brewing
8 minutes' walk
Craft brewery known for its organic beers and relaxed vibe. Offers tours and tastings, with vegetarian options available.
Dr Phillips Center for the Performing Arts
20 minutes' walk
Cultural hub featuring musicals, concerts, and dance performances, providing a vibrant arts scene in a stunning venue.
Thornton Park
25 minutes' walk
Trendy area with bars, cafes, and shops offering nightlife options, including live music, perfect for a night out.
Getting around
City Centre
Orlando6 min  ·  500 m
Airports
Orlando Executive Airport (ORL)12 min  ·  7.4 km
Orlando International Airport (MCO)28 min  ·  18.1 km
Train
Church Street Station17 min  ·  1.4 km
Woodsmere Sub-Station15 min  ·  9.4 km
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site (reservation might be needed) at USD 18 per day.
Internet
is available in for free.
Breakfast
All visitors are offered a buffet breakfast for a fee. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are allowed on request.
Languages
Spanish
Number of floors:
6
Number of rooms:
126
FAQs
About Hampton Inn & Suites Orlando/Downtown South - Medical Center
What are the check-in and check-out times at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Check-in is at 15:00 and check-out is at 11:00.
Is parking available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Private parking is available on-site for 18 USD per day, and reservations are needed.
What amenities does Hampton Inn & Suites Orlando/Downtown South - Medical Center offer?
Popular amenities include a fitness center, outdoor swimming pool, business center, and free Wi-Fi.
Does Hampton Inn & Suites Orlando/Downtown South - Medical Center provide breakfast?
A complimentary continental breakfast is served daily from 7:00 AM to 10:00 AM on weekends.
How far is Hampton Inn & Suites Orlando/Downtown South - Medical Center from Orlando Executive Airport?
The hotel is 5 km from Orlando Executive Airport.
Are there any nearby attractions to Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Nearby attractions include Orange Avenue (2 km) and Universal Orlando Resort (approximately 16 km).
What room amenities are available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Rooms feature air conditioning, flat-screen TVs, small refrigerators, and coffee-making facilities.
Is there an outdoor pool at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Yes, there is an outdoor swimming pool open all year.
What business services are provided at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
The hotel offers meeting rooms, a business center, and conference facilities.
What restaurants are located near Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Nearby dining options include Lucy Bleuz Cafe and The Lucky Lure, both within 0.5 km.
Are there any recreational facilities at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
The hotel has a fitness center and outdoor pool for guest recreation.
Does Hampton Inn & Suites Orlando/Downtown South - Medical Center have laundry services?
Yes, laundry services are available for guests.

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